Welcome to the site !!
They should be the same , as long as the rear hub width from rotor to sprocket is the same , they should fit , I have a 20 450R and I am using my old wheels from my 02 450R with a 3.75mm spacer for the sprocket as a spare set , as that is the only difference from earlier years to later is they moved the sprocket over 3.75mm , so a spacer takes up that space and does not compromise anything , the physical hub part where the bearings are should be the same from 04 on , at least on the 450 , aside from the front rotor size as the earlier years were 240mm front rotor and now are 270mm , but that should be the same in your case
So front should fit no issues and if the rear is the same width between those 2 points then it should as well , so the 250 should fit from 16-21 , or from 04-21 for the front and depending on if they changed the rear hub like they did on the 16-21 450 ..... Hopefully that makes sense ...
