I ride mostly at Cal City. Here are my current SoCal winter settings. Your mileage may vary.
2005 450x
Airbox side vents opened and snorkel removed
Twin Air Powerflow filter
Smog crap removed
White Bros E2 with sparky quiet tip in
Stock Pilot (45)
Fuel Screw 2.5 turns out
Red tip JD needle with clip in the middle position
170 Main jet
I'll be going with the 48 pilot really soon so I don't have to back the fuel screw out so much due to this colder denser winter air.
Good luck!

Joe V. - Simi Valley, CA